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But as you begin to feel better and want to move on, how long should you keep taking the pills? Here's how to distinguish discontinuation symptoms from relapse: Discontinuation symptoms emerge within days to weeks of stopping the medication or lowering the dose, whereas relapse symptoms develop later and more gradually. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. They're generally not medically dangerous but may be uncomfortable. To learn what you can do to get the sleep you need for optimal health, safety, and well-being, buy the Harvard Special Health Report Improving Sleep: A guide to a good night's rest. In a meta-analysis of controlled studies, investigators at Harvard Medical School and other universities found that people who undergo psychotherapy while discontinuing an antidepressant are less likely to have a relapse.

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